From the error, it looks like your tenant has been deleted. Check the environment variable for the baseURL and if you are using the correct API key in the authentication.
GET /api/profiles?status=Active HTTP/1.1 and without filter works for me. If its a training tenant, then you should reach out to support team for further assistance.
It seems to me that if it is a tenant issue, it seems that SailPoint was going to configure some bases so that everything works as it should. We will discuss it with them to validate. Thanks for confirming that the API call works for you.